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ITEM | SPECIFICATION |
CHARACTERS: | YELLOW OR ORANGE CRYSTALLINE POWDER,ODOURLESS OR ALMOST ODOURLESS,INSOLUBLE IN WATER AND IN MOST ORGANIC SOLVENTS, DISSOLVES IN DILUTE ACIDS AND IN ALKALINE SOLUTION. |
IDENTIFICATION A:SPECIFIC ROTATION: B:ULTRAVIOLET ABSORBTION:
C:THIN-LAYER CHROMATOGRAPHY: |
SPECIFIC OPTICAL ROTATION:+18O TO + 22O A256:A365 : 2.8-3.0 IT EXHIBITS THREE MAXIUMA AT 256,283 AND 363nm THE A AT 256nm IS ABOUT 590,AT 283nm IS ABOUT 575,AT 365NM IS ABOUT 206. THE PRINCIPAL SPOT IN THE CHROMATOGRAM OBTAINED WITH SOLUTION SAMPLE IS SIMILAR IN POSITION,FLUORE SCENCE AND SIZE TO THAT IN THE CHROMATOGRAM OBTAIN WITH SOLUTION FOLIC ACID R S |
CHROMATOGRAPHIC PURITY: | THE SUM OF THE AREA OF ALL PEAKS IS NOT GREATER THAN 2.0% |
FREE AMINES:: | A2:A1≤1/6 |
RESIDUE ON IGNITION: | ≤0.3% |
ORGANIC VOLATILE IMPURITIES:: | MUST COMPLIES |
LOSS ON DRYING: | 5.0%-8.5% |
ASSAY(on dry basis): | 97.0%-102% |