ITEM

SPECIFICATION

CHARACTERS:

YELLOW OR ORANGE CRYSTALLINE POWDER,ODOURLESS OR ALMOST

ODOURLESS,INSOLUBLE IN WATER AND

IN MOST ORGANIC SOLVENTS,

DISSOLVES IN DILUTE ACIDS AND IN ALKALINE SOLUTION.

IDENTIFICATION

A:SPECIFIC ROTATION:

B:ULTRAVIOLET ABSORBTION:

C:THIN-LAYER CHROMATOGRAPHY:

SPECIFIC OPTICAL ROTATION:+18^O TO + 22^O

A256:A365 : 2.8-3.0

IT EXHIBITS THREE MAXIUMA AT 256,283 AND 363nm THE A AT 256nm IS ABOUT 590,AT 283nm IS ABOUT 575,AT 365NM IS ABOUT 206.

THE PRINCIPAL SPOT IN THE CHROMATOGRAM OBTAINED WITH SOLUTION SAMPLE IS SIMILAR IN POSITION,FLUORE SCENCE AND SIZE TO THAT IN THE CHROMATOGRAM OBTAIN WITH SOLUTION FOLIC ACID R S

CHROMATOGRAPHIC PURITY:

THE SUM OF THE AREA OF ALL PEAKS IS NOT GREATER THAN 2.0%

FREE AMINES::

A2:A1≤1/6

RESIDUE ON IGNITION:

≤0.3%

ORGANIC VOLATILE IMPURITIES::

MUST COMPLIES

LOSS ON DRYING:

5.0%-8.5%

ASSAY(on dry basis):

97.0%-102%